abstract：PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...

journal_title：Japanese journal of ophthalmology

authors： Suzuki Y,Nakazawa M,Suzuki K,Yamazaki H,Miyagawa Y

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To determine whether the time course of average visual recovery (visual gain curve) after vitrectomy for different macular diseases can be described by a mathematical function. METHODS:The medical records of 1951 eyes that underwent vitrectomy for different macular diseases such as macular hole, epiretinal mem...

journal_title：Japanese journal of ophthalmology

authors： Kumagai K,Ogino N,Larson E

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To analyze the characteristics and clinical manifestations of clinically diagnosed and serologically confirmed ocular toxocariasis in patients. METHODS:Thirty-three eyes of 33 patients diagnosed as having ocular toxocariasis at the Hallym University Medical Center between January 1999 and December 2008 were in...

journal_title：Japanese journal of ophthalmology

authors： Kwon SI,Lee JP,Park SP,Lee EK,Huh S,Park IW

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To investigate the utility values associated with visual loss due to age-related macular degeneration (AMD) in Japanese patients. METHODS:Utility values in 48 Japanese patients with bilateral exudative AMD were measured using the time trade-off and standard gamble methods. RESULTS:The time trade-off method ut...

journal_title：Japanese journal of ophthalmology

authors： Yanagi Y,Ueta T,Obata R,Iriyama A,Fukuda T,Hashimoto H

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To clarify the redox states of the aqueous humor and serum in senile cataract patients. METHODS:We analyzed the reduced and oxidized albumin fractions in 58 patients. The patients had no detectable evidence of other eye or systemic diseases and were divided into two age groups (53-75 and 76-96 years). Analysis...

journal_title：Japanese journal of ophthalmology

authors： Kawai K,Hayashi T,Matsuyama Y,Minami T,Era S

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To clarify the usefulness of measuring anterior chamber depth by the IOLMaster for early-stage assessment of the therapeutic effect of steroid pulse therapy in patients with Vogt-Koyanagi-Harada (VKH) syndrome with active uveitis. METHODS:Seven patients with VKH syndrome (three men and four women) participated...

journal_title：Japanese journal of ophthalmology

authors： Otsuki T,Shimizu K,Igarashi A,Kamiya K

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To determine whether photoreceptor degeneration in transgenic (Tg) rabbits carrying the Pro347Leu rhodopsin mutation alters the neural activity of the middle and inner retinal neurons. METHODS:Multifocal electroretinograms (mfERGs) were recorded from eight 12-week-old Tg rabbits both before and after intravitr...

journal_title：Japanese journal of ophthalmology

authors： Yokoyama D,Machida S,Kondo M,Terasaki H,Nishimura T,Kurosaka D

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:This study was performed to assess the impact of dry eye on patients' quality of life (QOL) and to analyze the association between subjective symptoms and ocular surface findings of dry eye. METHODS:The study population consisted of 158 patients with dry eye aged 20 years or older who visited any of the 15 med...

journal_title：Japanese journal of ophthalmology

authors： Mizuno Y,Yamada M,Miyake Y,Dry Eye Survey Group of the National Hospital Organization of Japan.

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To investigate the efficacy of intravitreal bevacizumab for the treatment of idiopathic macular telangiectasia (IMT). METHODS:Ten eyes of eight consecutive patients with IMT were studied. Four eyes had type 1, and six had type 2 IMT according to Yannuzzi's classification. All patients were treated with intravi...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Yuzawa M

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To assess intravitreal bevacizumab (IVB) for choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Japanese patients. METHODS:Forty-seven patients treated with IVB for newly diagnosed subfoveal or juxtafoveal CNV (predominantly classic CNV, 15 eyes; minimally classic CNV, 11...

journal_title：Japanese journal of ophthalmology

authors： Suzuki M,Gomi F,Sawa M,Tsujikawa M,Sakaguchi H

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Epidermal nevus syndrome encompasses a group of congenital neurocutaneous anomalies characterized by epidermal nevi in association with cerebral, ocular, and skeletal abnormalities. We report herein the case of a Japanese girl with epidermal nevus syndrome associated with complex ocular choristoma and discus...

journal_title：Japanese journal of ophthalmology

authors： Miyagawa Y,Nakazawa M,Kudoh T

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To establish human corneal stroma- and sclera-derived cells as models for studying diseases of the anterior segment of the eye. METHODS:Using a recombinant retrovirus system, we transfected human papilloma virus 16 E6 and E7 (HPV16 E6/E7) into human corneal stroma- and sclera-derived cells. The primary cells a...

journal_title：Japanese journal of ophthalmology

authors： Kashiwagi Y,Nishitsuka K,Namba H,Kamiryo M,Takamura H,Yamashita H

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To determine alterations of the photopic negative response (PhNR) in the full-field and focal macular electroretinograms (ERGs) of patients with optic nerve atrophy (ONA). METHODS:Ten eyes of eight patients, five women and three men with a mean age of 55.1 years, with ONA were studied. Thirty-six age-matched c...

journal_title：Japanese journal of ophthalmology

authors： Tamada K,Machida S,Yokoyama D,Kurosaka D

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:This study examines the impact of cataracts on health-related quality of life (HR-QOL) and health events in the older population. METHODS:The study population consisted of 439 unoperated cataract patients aged 60 years or older who visited any of the facilities affiliated with the Cataract Survey Group of the ...

journal_title：Japanese journal of ophthalmology

authors： Yamada M,Mizuno Y,Miyake Y,Cataract Survey Group of the National Hospital Organization of Japan.

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To compare endothelial damage of the donor cornea in relation to the method of inserting the donor cornea into the recipient anterior chamber during Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:Fifteen enucleated pig eyes were used. The donor corneoscleral buttons were mounted in an a...

journal_title：Japanese journal of ophthalmology

authors： Hwang H,Kim M

更新日期：2009-09-01 00:00:00

abstract：:We have adapted intrinsic signal optical imaging of neural activity to the noninvasive functional imaging of the retina. Results to date demonstrate the feasibility and potential of this new method of functional assessment of the retina. In response to visual stimuli, we have imaged reflectance changes in the retina t...

journal_title：Japanese journal of ophthalmology

authors： Ts'o D,Schallek J,Kwon Y,Kardon R,Abramoff M,Soliz P

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To evaluate the relation between higher order aberrations (HOAs) and contrast sensitivity function (CSF) in a population with myopia. METHODS:In this case series, HOAs were measured in 70 myopic eyes over a 6-mm pupil. Contrast sensitivity was also measured. From the contrast sensitivity data, the area under t...

journal_title：Japanese journal of ophthalmology

authors： Feizi S,Karimian F

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To investigate the prevalence of superior segmental optic nerve hypoplasia in Korea. METHODS:We reviewed the fundus photographs of 3905 individuals who were 40 years old or older and who participated in the comprehensive medical examination program at the Health Promotion Center of Seoul National University Bu...

journal_title：Japanese journal of ophthalmology

authors： Han SB,Park KH,Kim DM,Kim TW

更新日期：2009-05-01 00:00:00

abstract：:Takayasu disease was first reported in 1908 by Mikito Takayasu as "a case of peculiar changes in the central retinal vessels." Because in these patients the pulse of the radial artery is impalpable, investigations focusing on the ischemic symptoms of the upper body were conducted. In 1948, Shimizu and Sano named this ...

journal_title：Japanese journal of ophthalmology

authors： Sugiyama K,Ijiri S,Tagawa S,Shimizu K

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:To determine whether exposure to ozonated solution alters the morphology of corneal endothelial cells in rats and to examine the protective effect of ascorbic acid. METHODS:The anterior chambers of rat eyes were filled with 4 ppm of ozonated solution. Some were left in that state, while others were flushed out...

journal_title：Japanese journal of ophthalmology

authors： Suzuki H,Sato S,Murano N,Matsui H,Oharazawa H,Takahashi H

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to experimentally investigate changes in visible light-induced photo-oxidation and to evaluate the inhibitory effect of various acrylic tinted intraocular lenses (IOLs) on photooxidation. METHODS:Three types of nontinted (VA-60BB, HOYA; SA60AT, Alcon; AU-6, Menicon) and tinted (YA-60B...

journal_title：Japanese journal of ophthalmology

authors： Mukai K,Matsushima H,Sawano M,Nobori H,Obara Y

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To compare color Doppler imaging (CDI) parameters of the superior ophthalmic vein (SOV) in patients with Graves' orbitopathy (GO) and in normal controls. METHODS:Forty-three GO patients and 14 normal controls underwent CDI of the SOV. Patients had either fibrotic (lipogenic or myogenic) or congestive orbitopat...

journal_title：Japanese journal of ophthalmology

authors： Monteiro MLR,Angotti-Neto H,Benabou JE,Betinjane AJ

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:To assess the changes in the size of muscle fibers and the composition of myosin heavy chain (MyHC) isoforms in the global layer (GL) and the orbital layer (OL) of rabbit rectus extraocular muscle (EOM) after recession. METHODS:The right superior rectus muscles of two rabbits were harvested at 3 days or 1, 2, ...

journal_title：Japanese journal of ophthalmology

authors： Park SC,Kim YT,Kim SA,Oh SY

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To compare the accuracy of postoperative pachymetry between Orbscan II (Bausch & Lomb) scanning-slit corneal topography/pachymetry and the Pentacam (Oculus) rotating Scheimpflug camera. METHODS:Central corneal thickness (CCT) was determined in 24 patients (48 eyes) before and after laser in situ keratomileusis...

journal_title：Japanese journal of ophthalmology

authors： Matsuda J,Hieda O,Kinoshita S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:We present the pathological findings at orbital exenteration in a patient with Wyburn-Mason syndrome who underwent transarterial embolization. CASE:A 31-year-old man with a 10-year history of gradual exacerbation of left exophthalmos and left cheek swelling was found to have facial and orbital arteriovenous...

journal_title：Japanese journal of ophthalmology

authors： Matsuo T,Yanai H,Sugiu K,Tominaga S,Kimata Y

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To study the effects of epigenetic events on corneal barrier functions, we examined tight junctions (TJs), the most important factor in the barrier function of the cornea, by using in vitro and in vivo corneal trauma models. METHODS:We examined alteration of TJ-associated gene expression and corneal barrier fu...

journal_title：Japanese journal of ophthalmology

authors： Nishikiori N,Sawada N,Ohguro H

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To investigate global protein expression profiles in the retinas of normal and glucocorticoid-induced ocular hypertensive rats by proteomic analysis. METHODS:Ocular hypertension was induced by topical application of dexamethasone (DEX) for 4 weeks. Age-matched untreated rats served as controls. Intraocular pre...

journal_title：Japanese journal of ophthalmology

authors： Miyara N,Shinzato M,Yamashiro Y,Iwamatsu A,Kariya KI,Sawaguchi S

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS). METHODS:Genomic DNA was isolated from leukocytes of 29 male patients with X-linked juvenile retinoschisis, 38 female carriers, and 100 normal controls. All 6 exons of the RS1 gene were ampli...

journal_title：Japanese journal of ophthalmology

authors： Ma X,Li X,Wang L

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To study proteomic changes in human lens epithelial cells (HLECs) exposed to 1800-MHz Global System for Mobile Communication (GSM)-like microwaves. METHODS:In three separate experiments, HLECs were exposed and sham-exposed (six dishes each) to 1800-MHz GSM-like radiation for 2 h. The specific absorption rates ...

journal_title：Japanese journal of ophthalmology

authors： Li HW,Yao K,Jin HY,Sun LX,Lu DQ,Yu YB

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To report a patient with agenesis of both internal carotid canals who presented with incomplete oculomotor palsy with pupil sparing. METHODS:The incomplete oculomotor palsy was followed clinically, and the precise anatomical relation of the aneurysm to the subarachnoid oculomotor nerve was investigated during ...

journal_title：Japanese journal of ophthalmology

authors： Takahashi M,Kase M,Suzuki Y,Yokoi M,Kazumata K,Terasaka S

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). METHODS:Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were enrolled in this study. Tear samples from RCE ey...

journal_title：Japanese journal of ophthalmology

authors： Sakimoto T,Shoji J,Yamada A,Sawa M

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Malassezia species rarely cause keratitis, and, thus, the clinical manifestations of Malassezia keratitis are not well known. CASE:We report the clinical findings in a 70-year-old woman who complained of pain in her left eye. Slit-lamp biomicroscopy showed a corneal ulcer with irregular infiltration, which ...

journal_title：Japanese journal of ophthalmology

authors： Suzuki T,Hori N,Miyake T,Hori Y,Mochizuki K

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:Diabetic complications are associated with abnormality of the basement membranes. We have developed a light-scattering detection system (LSDS) specifically for measurement of light scattering at the corneal epithelial basement membrane, and have determined the reproducibility and clinical significance of the re...

journal_title：Japanese journal of ophthalmology

authors： Takahashi N,Wakuta M,Morishige N,Chikama T,Nishida T,Sumii Y

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To evaluate the cycloplegic effect of mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine in myopic children, and to determine whether their efficacy was associated with their clinical characteristics. METHODS:Eighty-one myopic children (age, mean +/- SD, 11.0 +/- 1.5 years; mean spherical equiv...

journal_title：Japanese journal of ophthalmology

authors： Hamasaki I,Hasebe S,Kimura S,Miyata M,Ohtsuki H

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:To identify a mutation in the PRPF31 gene in a family (Family K) with autosomal dominant retinitis pigmentosa (adRP) linked to 19q13.4 (RP11) and to find the frequency of mutations in the PRPF31 gene among Japanese families with adRP. METHODS:Genomic DNA specimens were prepared from five symptomatic and two as...

journal_title：Japanese journal of ophthalmology

authors： Taira K,Nakazawa M,Sato M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Schwannoma arising from the ciliary body is a rare intraocular neoplasm, and most cases previously reported were diagnosed histopathologically after eyeball enucleation because of a diagnosis of ciliary body melanoma. CASE:A case of ciliary body schwannoma was dissected locally. OBSERVATIONS:A 19-year-old ...

journal_title：Japanese journal of ophthalmology

authors： Goto H,Mori H,Shirato S,Usui M

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:To report optical coherence tomography (OCT) findings of macular edema secondary to retinal arterial macroaneurysms. METHODS:Six eyes with retinal arterial macroaneurysms were retrospectively examined by OCT. All eyes had macular edema without massive macular hemorrhage. Fluorescein angiography was performed i...

journal_title：Japanese journal of ophthalmology

authors： Takahashi K,Kishi S

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To evaluate dye retention in the fundus after indocyanine green (ICG)-assisted internal limiting membrane peeling. METHODS:Ten eyes with stage 3 or 4 nondiabetic idiopathic macular hole (MH group) and six eyes with diffuse diabetic macular edema (DM group) were studied. The fundus was examined with 780-nm infr...

journal_title：Japanese journal of ophthalmology

authors： Ashikari M,Ozeki H,Tomida K,Sakurai E,Tamai K,Ogura Y

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:The mortality rate of patients with retinoblastoma still varies in developing countries, and data for Asia and Taiwan are relatively scarce. In this retrospective study, we aimed to describe the survival characteristics and prognostic factors of 54 retinoblastoma cases diagnosed at the Taipei Veterans General H...

journal_title：Japanese journal of ophthalmology

authors： Chang CY,Chiou TJ,Hwang B,Bai LY,Hsu WM,Hsieh YL

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:To develop a novel method for measuring tear break-up time (BUT) by continuously measuring higher order wavefront aberrations using a Hartmann-Shack (H-S) aberrometer. METHODS:Wavefront aberrations up to the sixth order for a 4-mm pupil were measured in six eyes of six normal subjects using an H-S aberrometer....

journal_title：Japanese journal of ophthalmology

authors： Mihashi T,Hirohara Y,Koh S,Ninomiya S,Maeda N,Fujikado T

更新日期：2006-03-01 00:00:00